Wednesday, June 13, 2012

Obama doesn't dwell on first-term issues this time

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Sleep apnea linked to increased risk for carbohydrate craving among diabetics

Sleep apnea linked to increased risk for carbohydrate craving among diabetics [ Back to EurekAlert! ] Public release date: 13-Jun-2012
[ | E-mail | Share Share ]

Contact: Doug Dusik
ddusik@aasmnet.org
630-737-9700
American Academy of Sleep Medicine

Authors of study encourage physicians to screen diabetics for obstructive sleep apnea

DARIEN, IL Researchers in New Jersey are encouraging primary care physicians to screen for obstructive sleep apnea (OSA) in patients with Type 2 diabetes. They found that in a small sample of clinic patients, the risk for sleep apnea was high among diabetics compared with non-diabetics, and that sleep apnea appeared to be associated with carbohydrate craving.

Their study, being presented today at SLEEP 2012, screened 55 patients for diabetes, OSA and carbohydrate cravings. More than half of the patients were diabetic. Among the diabetic patients, the prevalence of OSA was 82 percent, and diabetics had almost double the risk of carbohydrate craving than non-diabetics. In addition, researchers found that patients with OSA were almost twice as likely to have high carbohydrate craving than patients without sleep apnea.

"This study provides an indication of the magnitude of the associated risk between sleep apnea and self-reported carbohydrate craving in the diabetic population," said study co-investigator Mahmood Siddique, DO, clinical associate professor of medicine at the Robert Wood Johnson Medical School in New Brunswick, N.J.

"Previous studies have shown that sleep deprivation may lead to changes in hormones that regulate appetite and hunger," Siddique said. "These hormonal changes can lead to significant craving for high-calorie carbohydrates such as cookies, candy, breads, rice and potatoes. The current study supports previous findings by validating this in a community sample of diabetics."

The study, conducted by the Sleep and Wellness Medical Associates LLC, is one of the first cross-sectional clinic-based studies to show an association between OSA and self-reported carbohydrate craving among patients with Type 2 diabetes.

"Current national guidelines on the management of diabetes need to consider sleep apnea as an independent risk factor more vigorously," said principal investigator Anthony Cannon, MD, American Diabetes Association regional president for central and southern Pennsylvania and southern New Jersey. "The management of patients with diabetes and or metabolic syndrome based solely on pharmacotherapy, exercise and nutritional modifications without taking into account the risk of sleep apnea may not lead to optimal outcomes for patients suffering from these chronic diseases."

"Clearly, a greater awareness among physicians is needed, as sleep apnea is often undiagnosed by primary care physicians," Cannon said. "Public policy can play a key role in the educational awareness of the association between sleep apnea and diabetes among both physicians and patients."

###

The abstract "Association of sleep apnea and carbohydrate craving among diabetics" is being presented today at SLEEP 2012, the 26th annual meeting of the Associated Professional Sleep Societies (APSS) in Boston. To be placed on the mailing list for SLEEP 2012 press releases or to register for SLEEP 2012 press credentials, contact AASM PR Coordinator Doug Dusik at 630-737-9700 ext. 9364, or at ddusik@aasmnet.org.

A joint venture of the American Academy of Sleep Medicine and the Sleep Research Society, the annual SLEEP meeting brings together an international body of more than 5,500 leading clinicians and scientists in the fields of sleep medicine and sleep research. At SLEEP 2012, more than 1,300 research abstract presentations will showcase new findings that contribute to the understanding of sleep and the effective diagnosis and treatment of sleep disorders such as insomnia, narcolepsy and sleep apnea.

Follow @aasmorg on Twitter for live updates and use the official hashtag #SLEEP2012 to see what attendees are saying. "Like" the American Academy of Sleep Medicine on Facebook at Facebook.com/sleepmedicine for photos, videos and more.


[ Back to EurekAlert! ] [ | E-mail | Share Share ]

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AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert! system.


Sleep apnea linked to increased risk for carbohydrate craving among diabetics [ Back to EurekAlert! ] Public release date: 13-Jun-2012
[ | E-mail | Share Share ]

Contact: Doug Dusik
ddusik@aasmnet.org
630-737-9700
American Academy of Sleep Medicine

Authors of study encourage physicians to screen diabetics for obstructive sleep apnea

DARIEN, IL Researchers in New Jersey are encouraging primary care physicians to screen for obstructive sleep apnea (OSA) in patients with Type 2 diabetes. They found that in a small sample of clinic patients, the risk for sleep apnea was high among diabetics compared with non-diabetics, and that sleep apnea appeared to be associated with carbohydrate craving.

Their study, being presented today at SLEEP 2012, screened 55 patients for diabetes, OSA and carbohydrate cravings. More than half of the patients were diabetic. Among the diabetic patients, the prevalence of OSA was 82 percent, and diabetics had almost double the risk of carbohydrate craving than non-diabetics. In addition, researchers found that patients with OSA were almost twice as likely to have high carbohydrate craving than patients without sleep apnea.

"This study provides an indication of the magnitude of the associated risk between sleep apnea and self-reported carbohydrate craving in the diabetic population," said study co-investigator Mahmood Siddique, DO, clinical associate professor of medicine at the Robert Wood Johnson Medical School in New Brunswick, N.J.

"Previous studies have shown that sleep deprivation may lead to changes in hormones that regulate appetite and hunger," Siddique said. "These hormonal changes can lead to significant craving for high-calorie carbohydrates such as cookies, candy, breads, rice and potatoes. The current study supports previous findings by validating this in a community sample of diabetics."

The study, conducted by the Sleep and Wellness Medical Associates LLC, is one of the first cross-sectional clinic-based studies to show an association between OSA and self-reported carbohydrate craving among patients with Type 2 diabetes.

"Current national guidelines on the management of diabetes need to consider sleep apnea as an independent risk factor more vigorously," said principal investigator Anthony Cannon, MD, American Diabetes Association regional president for central and southern Pennsylvania and southern New Jersey. "The management of patients with diabetes and or metabolic syndrome based solely on pharmacotherapy, exercise and nutritional modifications without taking into account the risk of sleep apnea may not lead to optimal outcomes for patients suffering from these chronic diseases."

"Clearly, a greater awareness among physicians is needed, as sleep apnea is often undiagnosed by primary care physicians," Cannon said. "Public policy can play a key role in the educational awareness of the association between sleep apnea and diabetes among both physicians and patients."

###

The abstract "Association of sleep apnea and carbohydrate craving among diabetics" is being presented today at SLEEP 2012, the 26th annual meeting of the Associated Professional Sleep Societies (APSS) in Boston. To be placed on the mailing list for SLEEP 2012 press releases or to register for SLEEP 2012 press credentials, contact AASM PR Coordinator Doug Dusik at 630-737-9700 ext. 9364, or at ddusik@aasmnet.org.

A joint venture of the American Academy of Sleep Medicine and the Sleep Research Society, the annual SLEEP meeting brings together an international body of more than 5,500 leading clinicians and scientists in the fields of sleep medicine and sleep research. At SLEEP 2012, more than 1,300 research abstract presentations will showcase new findings that contribute to the understanding of sleep and the effective diagnosis and treatment of sleep disorders such as insomnia, narcolepsy and sleep apnea.

Follow @aasmorg on Twitter for live updates and use the official hashtag #SLEEP2012 to see what attendees are saying. "Like" the American Academy of Sleep Medicine on Facebook at Facebook.com/sleepmedicine for photos, videos and more.


[ Back to EurekAlert! ] [ | E-mail | Share Share ]

?


AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert! system.


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air conditioning repair, ac filter - What Makes the Best Filter?











We all have air conditioning systems in our homes to keep us cool when the weather is too hot. These devices are very useful especially in the summer but one of the most important parts of the air conditioner is the ac filter because it is something that keeps pollutants and allergens from entering your home. It needs to be replaced at least once a month even when you do not use it because dirt can rest on it and it will spread throughout your home when you turn on your air conditioner. When you change your AC filter, make sure that you are changing it with something that filters most of the pollutants so you only get clean air.

The standard ac filter that comes with most air conditioning products does not do that good of a job. It only filters the bigger particles in the air which means that the tiny pollutants are still able to pass through it and enter your home. After a month of use, you should change your filter to something that is more capable when it comes to filtering.

An electrostatic filter is much similar to an electronic filter and they trap a huge percentage of the pollutants that are in the air. It uses electrical charges to draw in the pollutants so that it does not get through the filter. Because of its electric properties, it does not have to be changed as often as the standard filter but getting one cost more money.

The HEPA filter is the best filter out there which is also known as the High Efficiency Particulate Arresting filter. This type of filter removes almost all particles in the air that is more than 0.3 micrometers. This is very small already and no other filter can do a better job than the HEPA filter.

During hot summer months, people may pay high electricity bills in an attempt to cool off. However, introduction of solar air conditioning has come with a series of benefits that people should explore. As a result, the application can be widely applied to reduce electricity costs, especially in deserts or houses located in arid areas. Prior to investing in a solar air conditioning system, people should do comparisons to choose the best cooling appliances.

A heating, ventilation, and air conditioning (HVAC) system is among the major energy consumers in a modern home. For instance, over 50 percent of a household's energy expenditure is associated with HVAC systems. Therefore, people should take a number of steps to reduce this expenditure while promoting a healthier living environment. This is where a solar hvac system can come in handy. These can be active or passive solar air conditioning systems.

After purchasing the air conditioning systems that will cater for all their needs, individuals can then enjoy a series of benefits associated with these technological innovations.

People will spend less money on electricity. This technological innovation provides an unmatched energy-saving avenue.

The invention of solar air conditioning came with a myriad of advantages. Therefore, this is a must appliance for people who live in deserts or warm arid areas.

Hi, I am Cathy. Air Conditioning Repair Weston is a licensed and insured A.C repair company, serving the Weston area since 1990. Visit us at duct cleaning in Palmetto Estates?fl

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A study shows that 'mosaicism' is gaining ground in cancer research

A study shows that 'mosaicism' is gaining ground in cancer research [ Back to EurekAlert! ] Public release date: 12-Jun-2012
[ | E-mail | Share Share ]

Contact: Juan J. Gomez
juanj.gomez@cnio.es
34-917-328-000
Centro Nacional de Investigaciones Oncologicas (CNIO)

The study has demonstrated that genetic variability in the embryo may predispose to cancer in adult life

A study recently published in Nature Genetics provides new evidence that the genetic makeup of the embryo may cause the appearance of tumors in adult life. These results bear out the growing theory that some tumors may have an extremely early origin, tracing to the individual's embryonic development, while offering new clues to understand the genetic causes of certain kinds of cancer, and their prevention and treatment.

Researcher Francisco X. Real, head of the Epithelial Carcinogenesis Group at the Spanish National Cancer Research Centre (CNIO) took part in the study, which was led by Christian Hafner of the University of Regensburg, Germany.

A cell, when it divides, generates two other identical cells with the same characteristics and genetic material. Genetic mutations alterations in the genes can occur during the embryo's development, and will then be passed to the daughter cells in the division process. The result is an individual whose cells differ genetically. It has long been suspected that this phenomenon, known as mosaicism, could be linked to several types of cancer, but the scientific community has little information on the genetic alterations that underlie it.

The authors of the paper conducted an exhaustive genetic study of 67 patients with a number of congenital skin lesions leading to tumours (nevus sebaceous, NS). They also studied the Schimmelpenning syndrome (SS), in which tissues like the brain or eye are also affected.

Biopsies of these patients' lesions found for the first time mutations in genes of the RAS family (97% in cases of NS and 100% in SS) which encode proteins of key importance in cell division regulation, while analyses of lesion-free tissues, like cells of the mouth mucous, blood leukocytes, etc. found their gene sequence to be normal. Further, all the patients that developed tumours were also mosaic for this gene family.

The above results, and those of previous studies led by the CNIO group, show that these mutations, which are confined solely to the cells of the affected skin and, as congenital conditions, arise during embryonic development, are the genetic cause of these anomalies and predispose to the formation of tumours.

Analysing the genome of 57,000 people

A complete analysis of the genome of over 57,000 individuals, also published this week in Nature Genetics, lends weight to the theory that mosaicism of distant origin is more widely present in patients with tumours than cancer-free individuals.

This second study drew on the combined efforts of 189 researchers worldwide, including Francisco X. Real and fellow CNIO researcher Nria Malats, head of the Genetic and Molecular Epidemiology Group, under the leadership of scientists at the U.S. National Cancer Institute and Pompeu Fabra University in Barcelona.

It is from this variability in the genetic makeup of cells from the same individual that we get the idea of personal genomes, in the plural. "Some of these mutations imply an increased risk of cancer, so certain patients should have more frequent examination to check how their lesions are progressing," explains Real.

###


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AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert! system.


A study shows that 'mosaicism' is gaining ground in cancer research [ Back to EurekAlert! ] Public release date: 12-Jun-2012
[ | E-mail | Share Share ]

Contact: Juan J. Gomez
juanj.gomez@cnio.es
34-917-328-000
Centro Nacional de Investigaciones Oncologicas (CNIO)

The study has demonstrated that genetic variability in the embryo may predispose to cancer in adult life

A study recently published in Nature Genetics provides new evidence that the genetic makeup of the embryo may cause the appearance of tumors in adult life. These results bear out the growing theory that some tumors may have an extremely early origin, tracing to the individual's embryonic development, while offering new clues to understand the genetic causes of certain kinds of cancer, and their prevention and treatment.

Researcher Francisco X. Real, head of the Epithelial Carcinogenesis Group at the Spanish National Cancer Research Centre (CNIO) took part in the study, which was led by Christian Hafner of the University of Regensburg, Germany.

A cell, when it divides, generates two other identical cells with the same characteristics and genetic material. Genetic mutations alterations in the genes can occur during the embryo's development, and will then be passed to the daughter cells in the division process. The result is an individual whose cells differ genetically. It has long been suspected that this phenomenon, known as mosaicism, could be linked to several types of cancer, but the scientific community has little information on the genetic alterations that underlie it.

The authors of the paper conducted an exhaustive genetic study of 67 patients with a number of congenital skin lesions leading to tumours (nevus sebaceous, NS). They also studied the Schimmelpenning syndrome (SS), in which tissues like the brain or eye are also affected.

Biopsies of these patients' lesions found for the first time mutations in genes of the RAS family (97% in cases of NS and 100% in SS) which encode proteins of key importance in cell division regulation, while analyses of lesion-free tissues, like cells of the mouth mucous, blood leukocytes, etc. found their gene sequence to be normal. Further, all the patients that developed tumours were also mosaic for this gene family.

The above results, and those of previous studies led by the CNIO group, show that these mutations, which are confined solely to the cells of the affected skin and, as congenital conditions, arise during embryonic development, are the genetic cause of these anomalies and predispose to the formation of tumours.

Analysing the genome of 57,000 people

A complete analysis of the genome of over 57,000 individuals, also published this week in Nature Genetics, lends weight to the theory that mosaicism of distant origin is more widely present in patients with tumours than cancer-free individuals.

This second study drew on the combined efforts of 189 researchers worldwide, including Francisco X. Real and fellow CNIO researcher Nria Malats, head of the Genetic and Molecular Epidemiology Group, under the leadership of scientists at the U.S. National Cancer Institute and Pompeu Fabra University in Barcelona.

It is from this variability in the genetic makeup of cells from the same individual that we get the idea of personal genomes, in the plural. "Some of these mutations imply an increased risk of cancer, so certain patients should have more frequent examination to check how their lesions are progressing," explains Real.

###


[ Back to EurekAlert! ] [ | E-mail | Share Share ]

?


AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert! system.


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Arizona Special Election Voter Guide

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Apple announces Guided Access for iOS devices, offers expanded accessibility controls

Apple announces Guided Access for iOS devices

We didn't get a ton of details on this one during the keynote, but Apple has announced a new Guided Access feature for iOS that promises to let folks limit what sort of input their devices are able to respond to. Some examples given by Apple are a parent of an autistic child who could disable on-screen controls so they don't accidentally exit an app, a teacher who could prevent students from exiting a test app, or museums who could keep folks locked in to their own display apps. That includes the ability to confine touch input to certain parts of the screen, in addition to disabling the home button or touch input altogether.

Apple announces Guided Access for iOS devices, offers expanded accessibility controls originally appeared on Engadget on Mon, 11 Jun 2012 14:59:00 EDT. Please see our terms for use of feeds.

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Alarms Calgary - Alarms Calgary Systems Must Meet the ...

There are many people residing in Calgary who have recently decided to purchase alarms Calgary systems

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There are many people residing in Calgary who have recently decided to purchase alarms Calgary systems. The reality is, until one is being proactive about his or her house's security, it is quite difficult to feel comfy or have peace of mind at house. Fixing alarms Calgary system is considered to be general enough practice, but when an individual intends to find a great security system, it is very much significant to know what his or her exact needs. ?This will contribute him or her to find out the perfect alarm system for his or her home security.

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